Jewish Genetic Disease

Epidemics and immigrants have suffered a lethal association in the public mind, from the Irish in New York wrongly blamed for the cholera epidemic of 1832 and Chinese in San Francisco vilified for causing the bubonic plague in 1900, to Haitians in Miami stigmatized as AIDS carriers in the 1980s. Silent Travelers vividly describes these and many other episodes of medicalized prejudice and analyzes their impact on public health policy and beyond. The book shows clearly how the equation of disease with outsiders and illness with genetic inferiority broadly affected not only immigration policy and health care but even the workplace and schools. The first synthesis of immigration history and the history of medicine, Silent Travelers is also a deeply human story, enriched by the voices of immigrants themselves. Irish, Italian, Jewish, Latino, Chinese, and Cambodian newcomers among others grapple in these pages with the mysteries of modern medicine and American prejudice. Anecdotes about famous and little-known figures in the annals of public health abound, from immigrant physicians such as Maurice Fishberg and Antonio Stella who struggled to mediate between the cherished Old World beliefs and practices of their patients and their own state-of-the-art medical science, to "Typhoid Mary" and the inspiring example of Mother Cabrini. Alan M. Kraut tells of the newcomers founding of hospitals to care for their own the "Halls of Great Peace" (actually little more than hovels where lepers could go to die) set up by Chinese immigrants; the establishment of St. Vincent's Hospital in New York as an institution sensitive to the needs of Catholic patients; and the creation of a tuberculosis sanitarium inDenver by Eastern European Jewish tradespeople who managed to scrape together $1.20 in contributions at their first meeting.

Janet Reibstein's mother and two aunts grew up in New Jersey amid a close-knit, extended Jewish family set apart only by a genetic propensity for breast cancer. Over fifty years, the disease claims Janet's two aunts, then her mother, then a cousin. Finally Janet must face the far-reaching decision of whether to undergo a preemptive mastectomy herself. A history of the disease in America as well as a story of sisters, mothers and daughters, and the men who love them, "Staying Alive is ultimately a tale of extraordinary strength and of the power of love in survival.

Genetic disorder - A genetic disorder, or genetic disease is a disease caused by abnormal expression of one or more genes in a person causing a clinical phenotype. There are a number of possible causes for genetic defects:

Glycogen storage disease type II - Glycogen storage disease type II (also called Pompe disease or acid maltase deficiency) is a rare genetic disorder caused by a deficiency in the enzyme acid alpha-glucosidase (GAA), which is needed to break down glycogen, a stored form of sugar used for energy. It is the only glycogen storage disease with a defect in lysosomal metabolism, and was the first glycogen storage disease to be identifiedâ€”in 1932.

Glycogen storage disease type I - Glycogen storage disease type I or von Gierke's disease, is the most common of the glycogen storage diseases. This genetic disease results from deficiency of the enzyme glucose-6-phosphatase.

Sickle-cell disease - Sickle cell disease is a general term for a group of genetic disorders caused by sickle hemoglobin (Hgb S). In many forms of the disease, the red blood cells change shape upon deoxygenation because of polymerization of the abnormal sickle hemoglobin.

jewishgeneticdisease

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